Leading Centre for world class Assisted Reproductive Services in Nigeria.

Microfluidic Sperm Sorting

Microfluidic Sperm Sorting

Microfluidic Sperm Sorting

What Is Microfluidic Sperm Sorting?

This is a chemical free method of selecting sperms using a disposable chip. It is a new gentle alternative for sperm processing which has been shown to reduce DNA Fragmentation (DFI) in sperms with high DNA fragmentation to nearly undetectable levels.
One of the common cause of high Sperm DNA fragmentation (High DFI) is the generation of Reactive Oxygen Species (ROS) due to oxidative stress. This ROS could be generated during the process of Centrifugation which is involved in Sperm Preparation for use during the IVF/ICSI procedure.
Microfluidic sperm sorting does not require centrifugation and as such limits the possibility of the generation of ROS during sperm preparation for treatment. Some studies have shown that frequent ejaculation, use of antioxidants and TESA could help reduce high DFI. Frequent ejaculation and TESA have recorded some positive results so far. Studies have suggested that High DFI is associated with low fertilization rates, poor embryo quality and development, poor blastulation and decreased pregnancy rates especially for DFI results above 25%.

How Does Microfluidic Sperm Sorting Work?

Raw sperm is introduced into the inflow and only motile and morphologically normal sperm are able to swim through the chip to the outflow where it is collected for use.

Benefits of Microfluidic Sperm Sorting?

It works based on the principle of natural sperm selection imitating the natural environment of the female reproductive system. The selected sperms have better morphology, genetic quality and double the viability and motility of unsorted sperms.
From a study conducted in our clinic using the Microfluidic sperm sorting method and the Bilayer method, we observed a significant reduction in DFI and increase in Fertilization, Cleavage and Blastulation rates with the Microfluidic Sperm sorting method.

Contact Us

For more information about Microfluidic Sperm Sorting at Nordica Fertility Centre Speak to the booking team on: 01 - 4667360, 01 - 4532266 or mail us on info@nordicalagos.org

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