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Understanding Uterine Fibroids and Fertility

Understanding Uterine Fibroids and Fertility

Uterine Fibroids icon. Vector illustration flat design

Uterine Fibroid (or Fibroid) are noncancerous growth on the muscles of the uterus which sometimes cause severe abdominal pain and heavy period when the tumour becomes quite large. It is present in about 70% of women in a lifetime and about 40% of especially black women in reproductive age group. It is a common gynaecological condition, but most women don’t notice they have fibroids because there are no symptoms but realize afterwards when the tumour grows.
The most common symptom will be heavy menstrual flow and can increase the risk of miscarriages in certain circumstances. In the United States, it cost about 34billion USD every year to treat fibroids. The cause of fibroid is unknown but can be traced to the genes, it runs in families and can be linked to female hormones (Estrogen and Progesterone) also.

Types of uterine fibroids

There are three main types of fibroids

  • Submucous Fibroid: It grows inside the uterus, in the endometrium where the baby stays.
  • Intramural Fibroid: It grows between the muscles of the uterus.
  • Subserosal Fibroid: It grows outside the uterus. As they grow larger, they can cause pain due to their size or pressure put on a nearby organ.
    Pedunculated fibroids are uterine growth attached to the uterine wall by a peduncle, a stalk-like growth. It is common with Submucous and Subserosal fibroid.

Symptoms of fibroids

Fibroids are usually without symptoms, but the growth in the size of tumor, the location and the number of fibroids can lead to the commonest symptoms.

  • Heavy menstrual flow. Sometimes the period comes with pain because the uterus is trying to get rid of the tumour.
  • Because of the size of these tumours, they compress and affect the organ surrounding the uterus making the patient pass water frequently at times.
  • It can also result in recurrent miscarriage, preterm labour, bleeding in between periods and malpresentation. Malpresentation can affect delivery making the baby not being able to come out with the head downwards, it either comes out with the buttocks or any other part of the body.

Diagnosis of fibroid

Fibroid can be diagnosed with different methods; examples are physical imaging (ultrasound), magnetic resonance imaging (MRI) and hysteroscopy. Hysteroscopy can be used to diagnose and also treat fibroid. This procedure allows a doctor look inside the uterus in order to diagnose and treat the causes of abnormal bleeding. It is very useful for submucous fibroid that stays inside the lining of the uterus.

Intersection between fibroids and infertility

Fibroids on their own rarely cause infertility, a lot of people feel fibroids, is the cause of their infertility. The American Society for Reproductive Medicine says, you see fibroids in about 5-10% of women suffering from infertility, but as a sole cause of infertility, fibroids only account 1% – 2.4%. For fibroids to cause infertility it’s either blocking the two tubes, (the tubes entering the uterus) or the tumour has grown big to occupying where the baby is supposed to be, (that is the submucous fibroids). It also affects implantation influencing the movement of the sperm and the egg in the tube and blocking tubes affecting when implantation will take place either by changing the shape and affecting the receptivity of the uterus to the fertilized egg.
Fibroids rarely cause infertility but can increase the risk of pregnancy losses, so thorough assessment should be carried out before any conclusions. Fibroids might be associated with adhesions in the pelvis that is scar tissues. When fertility is affected by uterine fibroids, the only treatment is to perform surgery to remove the tumour, because when infertility is also part of the equation, drugs don’t help, most of these drugs stop menstruation and ovulation. It’s not all fibroids that need to be removed, every fibroid must be properly assessed by a gynaecologist who is experienced to advise on what’s proper to do.

Surgeries performed to remove fibroid

  1. Minimally Invasive Surgery (keyhole)

    It is a method of carrying out an operation without having to make a large incision. The best way to remove the fibroid in the cavity of the uterus is through hysteroscopy. It can deal only with the fibroid inside the cavity of the uterus, and once there’s fibroid in the wall of the uterus, hysteroscopy alone won’t work.
    All evidence shows that the most terrible fibroids with fertility are the ones in the cavity of the uterus. The ones on the walls of the uterus can also reduce fertility, but need to get to a particular size. That why assessment is very important.

  2. Laparoscopy

    It is a surgical procedure to examine the organs inside the abdomen. The best way to remove the fibroid on the walls of the uterus, which we call the intramural or the ones on the outside of the uterus is through laparoscopy. The conventional open myomectomy which is the abdominal myomectomy can also be performed. But the most important thing is that the doctor needs to know the limitations and what to chase. It is even better to perform hysteroscopy after the intramural fibroids have been removed. With the constant growth in the medical world, laparoscopic-assisted abdominal myomectomy was developed. This is when you combine laparoscopy with the conventional myomectomy for fibroid removal.

  3. Uterine Fibroid Embolization

    It is a minimally invasive procedure used to treat fibroid tumour of the uterus, some particles (embolic agents) like beads are inserted into the artery of the uterus, causing the fibroid to shrink.

  4. Magnetic Resonance-guided Focused Ultrasound

    Still coming up, high intensity focused ultrasound is used to shrink the size of the fibroid with this procedure.

 

 

Frequently Asked Questions About Fibroids

How can fibroid affect fertility?

It affects implantation, either by affecting the movement of the sperm and egg in the tube, or blocking tubes or either by affecting the implantation process by either changing the blood supply or changing the shape and affecting the receptivity of the uterus to the fertilized egg.

After removal of fibroid, can the effect of fertility be improved?

Yes, we might be sure on one end and not sure on the other end depending on the type of fibroid the patient suffers. For submucous fibroids, there is no doubt that any size of fibroid attached to the cavity of the uterus will affect fertility and it should be removed. A lot of people give birth without removing their fibroids, but when they are big, they can actually affect implantation. Removing fibroids when implanted in infertility can improve the chance of getting pregnant.

Can fibroid grow back?

The unfortunate answer is yes, in 15-51% of patients, fibroids grow back, after removal of fibroids, it is important to do something about fertility because it can come back.

 

What if you remove fibroids, can the effect of fertility be restored?

Yes, we might be sure on one end and not be on the other. For submucous fibroids, however, there is no doubt that any size of submucous fibroid attached to the cavity of the uterus will affect fertility and it should be removed using hysteroscopy. The ones that are in the wall of the uterus which we call intramural of up to 4-5cm do not need to be bothered about. A lot of people give birth without removing their fibroids, but when they are big, they can actually affect implantation.

How long can you wait after fibroid surgery before you can attempt to get pregnant?

From about 6 weeks if you did the hysteroscopic surgery, especially if you are planning to do IVF and about 3 months if you did abdominal surgery. The type of surgery will affect the time basically. The myth that you have to wait for 1-2 years is not true; the very worst will be about 3-6 months.

Can fibroid grow back?

The unfortunate answer is yes, in 15-51% of patients, fibroids grow back. When you remove fibroids, it is important that you do something about it quickly because it can come back.

If people get pregnant with fibroids, does it have any effect on pregnancy?

Yes, there is:
• The incident of the placenta separating during delivery -abruption could happen and this can actually lead to fetal demise, so it is important that when you have fibroids and you are pregnant you get appropriate antenatal care and you are also vigilant in case of any pain that you cannot explain, you must go to the hospital immediately.
• It can also lead to abnormal growth of the baby because the blood supply might be affected.
• Preterm labour or delivery

In summary, there is no doubt that fibroids affect fertility, but as the sole cause of infertility, that is rare. Location is the most important thing when talking about fertility and fibroids. Undergoing surgery to remove fibroids when done carefully and appropriately increase the pregnancy rate. However, because the treatment of uterine fibroid itself might lead to infertility and difficulty in the treatment of infertility; it is always advisable to tread with caution.

An experiment was carried out where, 3000 women who had hysteroscopy about 61% of them had abnormalities in their endometrium and 50% of this 61 % was due to the treatment of fibroids, that is why it is not every fibroid that needs to be removed if you remove fibroids that do not need to be removed you might end up with a bigger problem, like the scarring of the endometrium. This is why it is important that you get good evaluation and an experienced gynaecologist who is knowledgeable about fertility-related issues.

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